Not medical advice. Sylva indexes traditional, fringe, and emerging remedies — including ideas mainstream medicine has rejected. Talk to a clinician before changing any treatment.

The library

28 remedies, honestly labeled.

Every entry is tagged by tier of evidence — from controlled trials to folk tradition. Filter by ailment or search by name.

Clinical evidence

Prolonged Fasting

Universal traditional practice

48–120 hour fasts trigger autophagy and stem-cell regeneration. Valter Longo's lab shows fasting-mimicking diets reduce chemotherapy toxicity and may slow tumor growth.

CancerDiabetesInflammationCognitive decline
Clinical evidence

Ashwagandha

Indian Ayurveda, 3000+ years

An adaptogen with strong RCT evidence for cortisol reduction, anxiety relief, and sleep quality. Some trials match low-dose benzodiazepines.

AnxietyInsomniaCognitive decline
Preliminary research

Lion's Mane Mushroom

East Asian traditional medicine

Contains hericenones and erinacines that cross the blood-brain barrier and stimulate nerve growth factor (NGF). Small trials show cognitive improvement in mild dementia.

Cognitive declineDepression
Preliminary research

Methylene Blue

First synthetic drug, 1876

An old industrial dye repurposed as a mitochondrial enhancer. Low doses are being studied for Alzheimer's, frontotemporal dementia, and treatment-resistant depression.

Cognitive declineDepression
Preliminary research

Hyperbaric Oxygen Therapy

Naval diving medicine, 1930s

Pressurized 100% oxygen forces oxygen into hypoxic tissues. Approved for wounds and decompression sickness; off-label use spans long-COVID, brain injury, and tumor sensitization.

CancerCognitive declineInflammation
Clinical evidence

Sulforaphane (Broccoli Sprouts)

Johns Hopkins — Paul Talalay, 1992

The most potent natural Nrf2 activator known. 3-day-old broccoli sprouts contain 20–50× more glucoraphanin than mature broccoli. Trials cover prostate cancer, autism, and air-pollution detox.

CancerCognitive declineInflammation